Mesembrine
One of the major alkaloids in Sceletium. It is commonly discussed as part of the mood and stress-support profile of the plant, and is often associated with clearer, more uplifted daytime feel in some product profiles.
Certificate of Analysis
Sceletium Alkaloid Lab Test Data
This page summarizes alkaloid assay data from Oxidative Stress Research Centre (CPUT). Values are reported as mg/g.
| Sample | Mesembrine | Mesembrenone | Δ7-Mesembrenone | Other Alkaloids | Total Alkaloids |
|---|---|---|---|---|---|
| Sceletium A | 44.17 | 5.14 | 1.18 | 0.43 | 50.91 |
| Sceletium B | 47.31 | 6.43 | 1.86 | 0.84 | 56.44 |
How to Read This Test
Mesembrenone
Another key alkaloid measured in the profile. It is often described as contributing to calmer, steadier support characteristics, especially when considered alongside mesembrine and related compounds.
Δ7-Mesembrenone
A closely related alkaloid measured separately. Its value helps complete the chemical fingerprint and is useful when comparing batches for consistency.
Other Alkaloids
Combined amount of additional alkaloids detected outside the primary named compounds.
Total Alkaloids
The sum of measured alkaloids in mg/g. Higher values indicate higher total alkaloid concentration for that sample.
Why the Profile Matters
Sceletium effects are not driven by a single compound. The relative balance between mesembrine, mesembrenone, Δ7-mesembrenone, and minor alkaloids can influence how a batch feels in practice. That is why we focus on both total alkaloid levels and profile consistency, not just one headline number.
Test Context
Laboratory: Oxidative Stress Research Centre, CPUT
Centre Manager: Prof. Jeanine Marnewick | Lab Manager: Fanie Rautenbach
Analysed by: G.S. Rautenbach | Authorised by: J.L. Marnewick
Method: Patnala, S, Kanfer, I. (2010). HPLC Analysis of Mesembrine-Type Alkaloids in Sceletium Plant Material Used as An African Traditional Medicine. Journal of Pharmacy & Pharmaceutical Sciences, 13(4), 558.
Sample Preparation: 100mg extracted in 10mL MeOH.
Note: N.D. = none detected.
This report applies to specific tested samples and is not automatically representative of every batch or all similar products. For official report-use restrictions and legal terms, refer to the original certificate language issued by the testing laboratory.
Interpretation notes on this page are educational summaries intended to make the assay easier to understand. They are not medical claims and do not replace professional healthcare guidance.